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alpha TTP antibody [C2C3], C-term

GTX108286
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHamster, Human, Mouse, Rat
TargetTTPA
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Overview

  • Supplier
    GeneTex
  • Product Name
    alpha TTP antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7274
  • Target name
    TTPA
  • Target description
    alpha tocopherol transfer protein
  • Target synonyms
    alpha-tocopherol transfer protein; alphaTTP; alpha-TTP; ATTP; AVED; tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency); TTP1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP49638
  • Protein Name
    Alpha-tocopherol transfer protein
  • Scientific Description
    This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa. [provided by RefSeq]
  • Reactivity
    Hamster, Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Self-assembled alpha-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier. Aeschimann W et al., 2017 Jul 10, Sci Rep
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  • alpha-Tocopherol transfer protein is not required for the discrimination against gamma-tocopherol in vivo but protects it from side-chain degradation in vitro. Grebenstein N et al., 2014 May, Mol Nutr Food Res
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  • alpha-Tocopherol and lipid profiles in plasma and the expression of alpha-tocopherol-related molecules in the liver of Opisthorchis viverrini-infected hamsters. Laothong U et al., 2013 Apr, Parasitol Int
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