ProductsBack/alpha TTP antibody [C2C3], C-term

alpha TTP antibody [C2C3], C-term

Name: alpha TTP antibody [C2C3], C-term
SKU: GTX108286_G10
Availability: BackOrder

GTX108286

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHamster, Human, Mouse, Rat

TargetTTPA

Overview

Supplier
GeneTex
Product Name
alpha TTP antibody [C2C3], C-term
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID7274
Target name
TTPA
Target description
alpha tocopherol transfer protein
Target synonyms
ATTP, AVED, TTP1, alphaTTP, alpha-tocopherol transfer protein, alpha-TTP, tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency)
Host
Rabbit
Isotype
IgG
Protein IDP49638
Protein Name
Alpha-tocopherol transfer protein
Scientific Description
This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa. [provided by RefSeq]
Reactivity
Hamster, Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Aeschimann W, Staats S, Kammer S, et al. Self-assembled α-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier. Sci Rep. 2017,7(1):4970. doi: 10.1038/s41598-017-05148-9
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Grebenstein N, Schumacher M, Graeve L, et al. α-Tocopherol transfer protein is not required for the discrimination against γ-tocopherol in vivo but protects it from side-chain degradation in vitro. Mol Nutr Food Res. 2014,58(5):1052-60. doi: 10.1002/mnfr.201300756
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Laothong U, Pinlaor P, Boonsiri P, et al. α-Tocopherol and lipid profiles in plasma and the expression of α-tocopherol-related molecules in the liver of Opisthorchis viverrini-infected hamsters. Parasitol Int. 2013,62(2):127-33. doi: 10.1016/j.parint.2012.11.002
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