
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA598875(ALS2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200)
ALS2 Antibody
CSB-PA598875
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetALS2
Overview
- SupplierCusabio
- Product NameALS2 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID57679
- Target nameALS2
- Target descriptionalsin Rho guanine nucleotide exchange factor ALS2
- Target synonymsALS2, alsin Rho guanine nucleotide exchange factor; ALS2CR6; alsin; ALSJ; amyotrophic lateral sclerosis 2 (juvenile); amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; amyotrophic lateral sclerosis 2 protein; IAHSP; PLSJ
- HostRabbit
- IsotypeIgG
- Protein IDQ96Q42
- Protein NameAlsin
- Scientific DescriptionThe protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203