ALS2 blocking peptide
GTX89837-PEP
Product group Proteins / Signaling Molecules
Overview
- SupplierGeneTex
- Product NameALS2 blocking peptide
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352202