Althiomycin [12656-40-5]

MedChem Express

Althiomycin [12656-40-5]

5

12656-40-5

Research Use Only

C16H17N5O6S2

439.47

Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active against Gram-positive bacteria, including S. aureus, S. epidermidis, and S. pyogenes (MICs=25, 25, and 3.1 microg/mL, respectively).2 Althiomycin inhibits protein synthesis in E. coli when used at concentrations of 1 and 10 microg/mL but not in isolated rabbit reticulocytes at 100 microg/mL.

O=C(C1=CSC(/C=N/O)=N1)NC(C2=N[C@@H](C(N3C(C=C(OC)C3)=O)=O)CS2)CO

12352200