Alvimopan

MedChem Express

Alvimopan [156053-89-3]

5

156053-89-3

Research Use Only

98.66

C25H32N2O4

424.53

Alvimopan (ADL 8-2698) is a potent, selective, orally active and reversible micro-opioid receptor antagonist, with an IC 50 of 1.7 nM. Alvimopan has selectivity for micro-opioid receptor ( K i =0.47 nM) over kappa- and delta-opioid receptors ( K i s=100, 12 nM, respectively). Alvimopan can be used for the research of postoperative ileus [1] [2] [3] .

O=C(CNC([C@@H](CC1=CC=CC=C1)CN2C[C@@H]([C@](C3=CC=CC(O)=C3)(CC2)C)C)=O)O

-20°C,2°C to 8°C

12352200