Alvimopan dihydrate

AbMole BioScience

Alvimopan dihydrate

9

170098-38-1

Chemical

Research Use Only

C25H36N2O6

460.56

Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible u-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan dihydrate has selectivity for u-opioid receptor (Ki=0.47 nM) over kappa- and delta-opioid receptors (Kis=100, 12 nM, respectively).

O.O.CC1CN(CCC1(C)C2=CC=CC(=C2)O)CC(CC3=CC=CC=C3)C(=O)NCC(O)=O

12352200