Alvimopan (monohydrate)

MedChem Express

Alvimopan (monohydrate) [1383577-62-5]

10

1383577-62-5

Research Use Only

99.18

C25H34N2O5

442.55

Alvimopan monohydrate (ADL 8-2698 monohydrate) is a potent, selective, orally active and reversible micro-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan monohydrate has selectivity for micro-opioid receptor (Ki=0.47 nM) over kappa- and delta-opioid receptors (Kis=100, 12 nM, respectively). Alvimopan monohydrate can be used for the research of postoperative ileus[1][2][3].

OC1=CC=CC([C@@]2(C)[C@@H](C)CN(C[C@H](CC3=CC=CC=C3)C(NCC(O)=O)=O)CC2)=C1.O

-20°C,2°C to 8°C

12352200