AM-0687 [1259522-94-5]
HY-120471
CAS Number1259522-94-5
Product group Chemicals
Molecular Weight442.45
Overview
- SupplierMedChem Express
- Product NameAM-0687 [1259522-94-5]
- Delivery Days Customer5
- CAS Number1259522-94-5
- CertificationResearch Use Only
- Molecular FormulaC23H19FN8O
- Molecular Weight442.45
- Scientific DescriptionAM-0687 is a selective inhibitor for PI3Kdelta with an IC50 of 2.9 nM. AM-0687 decreases the levels of IgG and IgM specific antibodies, inhibits the anti-IgM/CD40L-induced proliferation of human B cell (IC50=0.8 nM) and the phosphorylation of AKT (IC50=0.7 nM), and exhibits anti-inflammatory efficacy[1].
- SMILESO=C(C1=C(C2=NC=CC=C2)C([C@@H](NC3=NC=NC(N)=C3C#N)C)=NC4=CC=C(F)C=C14)NC
- UNSPSC12352200