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AM-6494

HY-128774
MedChem Express
CAS Number1874232-80-0
Product group Chemicals
Molecular Weight473.50
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AM-6494 [1874232-80-0]
  • Delivery Days Customer
    10
  • CAS Number
    1874232-80-0
  • Certification
    Research Use Only
  • Molecular Formula
    C22H21F2N5O3S
  • Molecular Weight
    473.50
  • Scientific Description
    AM-6494 is a potent and orally active BACE1 (efficacious beta-site amyloid precursor protein cleaving enzyme 1) inhibitor ( IC 50 =0.4 nM) with in vivo selectivity over BACE2 ( IC 50 =18.6 nM) [1] . AM-6494 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • SMILES
    O=C(C1=NC=C(OCC#C)N=C1)NC2=CC(F)=C(F)C([C@@]3(C)N=C(N)S[C@@]4(COC)C[C@@]34[H])=C2
  • UNSPSC
    12352200

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AM-6494 [1874232-80-0]
Product group Chemicals
TargetMol Chemicals
CAS Number1874232-80-0
Molecular Weight473.5
  • SizePrice