AM-9635 [1338483-10-5]

TargetMol Chemicals

AM-9635 [1338483-10-5]

72

Research Use Only

AM-9635

C19H14F2N8

392.36

AM-9635 is a potent and selective PI3Kdelta inhibitor. AM-9635 showes good cellular potency (in vitro pAKT IC50 = 4.2 nM ). AM-96352 inhibits KLH-specific IgG and IgM in a dosedependent manner AM-9635 is well tolerated at all doses and exhibits significantly reduced IgG and IgM specific antibodies . PI3Kalpha and PI3Kbeta are ubiquitously expressed and play a role in cell growth, division, and survival.

3 years

[C@H](NC=1C(C#N)=C(N)N=CN1)(C)C=2N(C=3C(N2)=CC=C(F)C3)C=4C=C(F)C=NC4

-20°C

12352200