Ambenoxan [2455-84-7]

MedChem Express

Ambenoxan [2455-84-7]

5

2455-84-7

Research Use Only

C14H21NO4

267.32

Ambenoxan is a skeletal muscle relaxant that acts on the central nervous system and is effective in mice, rats, rabbits, dogs, and monkeys without loss of the righting reflex. Ambenoxan has no peripheral neuromuscular blocking effects and significantly reduces or eliminates decerebrate rigidity in rabbits, but does not antagonize the effects of strychnine, leptazol, or tremorine. Like other central nervous system depressants, ambenoxan prolongs sleep duration in hexobarbitone, but it has no local anesthetic effects. In anesthetized cats, ambenoxan lowers blood pressure and reduces the pressor response to epinephrine, but has no effect on norepinephrine.

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12352200