Ambuic acid [340774-69-8]

TargetMol Chemicals

Ambuic acid [340774-69-8]

44

340774-69-8

Chemical

Research Use Only

Ambuic acid

C19H26O6

350.41

Ambuic acid is a cyclohexanone that has phytopathogenic antifungal, quorum sensing inhibitory, and antibacterial activities. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP) in E. faecalis, autoinducing peptide I (AIP-I) in S. aureus, and LsrD698 and LsrD826 in L. innocua. It suppresses abcess formation in a mouse model of skin infection induced by methicillin-resistant S. aureus (MRSA) when administered at a dose of 5 microg and decreases the activity of the agr quorum sensing system in an in vivo reporter assay.

3 years

CCCCC\C=C\C1=C(CO)[C@@H](O)[C@H]2O[C@@]2(C\C=C(/C)C(O)=O)C1=O

-20°C

12352200