Bio-Connect

AMCA-6-dUTP

ORB178359
Biorbyt
Estimated Purity≥95%
Product group Chemicals
Molecular WeightTheoretical MW: 851.58 g/mol (free acid); Detected MW: 851.16 g/mol (free acid)
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Overview

  • Supplier
    Biorbyt
  • Product Name
    AMCA-6-dUTP
  • Delivery Days Customer
    10
  • Application Supplier Note
    Incorporation into DNA/cDNA by: PCR with Taqpolymerasein-house data; Nick Translation with DNAse I/DNA Polymerase Iin-house data. Spectroscopic Propertie: lambdaexc 350 nm, lambdaem 450 nm, epsilon 19.0 L mmol-1 cm-1 (Tris-HCl pH 7.5).
  • Certification
    Research Use Only
  • Concentration
    1.0-1.1 mM
  • Estimated Purity
    ≥95%
  • Molecular Weight
    Theoretical MW: 851.58 g/mol (free acid); Detected MW: 851.16 g/mol (free acid)
  • Scientific Description
    AMCA-6-dUTP is recommended for direct enzymatic labeling of DNA/cDNA e.g. by PCR and Nick Translation. It is incorporated as substitute for its natural counterpart dTTP. The resulting Dye-labeled DNA/cDNA probes are ideally suited for fluorescence hybridization applications such as FISH or microarray-based gene expression profiling. Optimal substrate properties and thus labeling efficiency is ensured by an optimized linker attached to the C5 position of uridine. Recommended AMCA-6-dUTP/dTTP ratio for PCR and Nick Translation: 20-30% AMCA-6-dUTP/80-70% dTTP (PCR), 30-50% AMCA-6-dUTP/70-50% dTTP (Nick Translation).
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200