Amelparib (hydrochloride)

MedChem Express

Amelparib (hydrochloride)

14

Research Use Only

98.37

C19H26ClN3O3

379.88

Amelparib (JPI-289) hydrochloride is a potent, orally active, and water-soluble inhibitor of PARP-1. Amelparib hydrochloride inhibits PARP-1 activity (IC50 = 18.5 nM) and cellular PAR formation (IC50 = 10.7 nM). Amelparib hydrochloride is a potential neuroprotective agent. Amelparib hydrochloride has the potential for the research of acute ischaemic stroke[1].

O=C1NC2=C(C3=C1CCCN3)C(OCC)=CC(CN4CCOCC4)=C2.Cl

2°C to 8°C

12352200