Amfonelic acid [15180-02-6]

MedChem Express

Amfonelic acid [15180-02-6]

14

15180-02-6

Research Use Only

C18H16N2O3

308.33

Amfonelic acid (WIN-25978) is a highly selective dopamine reuptake inhibitor. Amfonelic acid interferes with the in vitro neuronal uptake of norepinephrine in the iris of rats, but does not alter the concentrations of norepinephrine or dopamine in the whole mouse brain. Amfonelic acid can be used as a pharmacological tool to study the brain reward system, dopamine pathway and dopamine transporter[1].

O=C(O)C1=CN(C2=NC(CC3=CC=CC=C3)=CC=C2C1=O)CC

12352200