AMG-487
ORB1146607
CAS Number473719-41-4
Product group Chemicals
Molecular Weight603.6
Overview
- SupplierBiorbyt
- Product NameAMG-487 [473719-41-4]
- Delivery Days Customer10
- CAS Number473719-41-4
- CertificationResearch Use Only
- Molecular FormulaC32H28F3N5O4
- Molecular Weight603.6
- Scientific DescriptionAMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) with IC50 values of 8nM and 8.2nM for I-IP-10 and I-ITAC, respectively. AMG 487 prevents the chemokines I-IP-10 and I-ITAC from binding to CXCR3. In the cellular assays, AMG 487 inhibits CXCR3-mediated cell migration with IC50 values of 8nM, 15nM and 36nM for I-IP-10, I-ITAC and MIG, respectively.
- SMILESCCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC=C(C=C5)OC(F)(F)F
- UNSPSC12352200
Related products
Product group Chemicals
AMG 487 [473719-41-4]FA104030
CAS Number473719-41-4
Molecular Weight603.59 g/mol
- SizePrice
![AMG 487 [473719-41-4]](https://www.targetmol.com/group3/M00/36/1C/CgoaEGayOBmEW8pCAAAAAK2YzAU172.png)
Product group Chemicals
AMG 487 [473719-41-4]T10297L
CAS Number473719-41-4
Estimated Purity99.89%
Molecular Weight603.59
- SizePrice
Product group Chemicals
AMG 487ORB1310006
CAS Number473719-41-4
Estimated Purity99.89%
Molecular Weight603.59
- SizePrice
Product group Chemicals
AMG 487 [473719-41-4]HY-15319
CAS Number473719-41-4
Estimated Purity99.80
Molecular Weight603.59
- SizePrice