Amicoumacin B [77674-99-8]

MedChem Express

Amicoumacin B [77674-99-8]

5

77674-99-8

CHEMICAL,general_chemicals_reagents

Research Use Only

C20H28N2O8

424.44

Amicoumacin B can be produced by actinomycete, strain 04-5195T.. Amicoumacin B increases the expression of bone morphogenetic protein 2 (BMP-2). Amicoumacin B has inhibitory effect against C. violaceum (MIC = 250 microg/mL). Amicoumacin B has quorum sensing inhibitory activity, and reduces the expression of the C. violaceum operons vioA, vioB, vioD, and vioE, but increases the expression of vioC[1][2].

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12352005