Amidepsine A [169181-28-6]

Name: Amidepsine A [169181-28-6]
SKU: AG-CN2-0109_A27
Availability: BackOrder

AG-CN2-0109

CAS Number169181-28-6

Product group Chemicals

Estimated Purity>95%

Molecular Weight567.6

Overview

Supplier
AdipoGen Life Sciences
Product Name
Amidepsine A [169181-28-6]
Delivery Days Customer
10
CAS Number
169181-28-6
Certification
Research Use Only
Estimated Purity
>95%
Hazard Information
Warning
Molecular Formula
C29H29NO11
Molecular Weight
567.6
Scientific Description
Chemical. CAS: 169181-28-6. Formula: C29H29NO11. MW: 567.6. Isolated from Humcola sp. FO-2942. Diacylglycerol acyltransferase (DGAT) inhibitor. Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders. - Diacylglycerol acyltransferase (DGAT) inhibitor [1-4]. Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
SMILES
COC1=CC(OC)=C(C(=O)OC2=CC(C)=C(C(=O)OC3=CC(C)=C(C(=O)NC(C)C(O)=O)C(O)=C3)C(O)=C2)C(C)=C1
Storage Instruction
2°C to 8°C,-20°C
UNSPSC
12352200

Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties: H. Tomoda, et al.; J. Antibiot. 48, 937 (1995)
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. II. Structure elucidation of amidepsines A, B and C: H. Tomoda, et al.; J. Antibiot. 48, 942 (1995)
Amidepsine E, an inhibitor of diacylglycerol acyltransferase produced by Humicola sp. FO-5969: H. Tomoda, et al.; J. Antibiot. 49, 929 (1996)
Potential therapeutics for obesity and atherosclerosis: inhibitors of neutral lipid metabolism from microorganisms: H. Tomoda & S. Omura; Pharmacol. Ther. 115, 375 (2007)