Aminooxy-PEG3-azide [1306615-51-9]

MedChem Express

Aminooxy-PEG3-azide [1306615-51-9]

10

1306615-51-9

Research Use Only

95.0

C8H18N4O4

234.25

Aminooxy-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-C2-PEG3-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Aminooxy-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

NOCCOCCOCCOCCN=[N+]=[N-]

-20°C

41115800