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Amiodarone-d4 (hydrochloride) [1216715-80-8]

HY-14188S
MedChem Express
CAS Number1216715-80-8
Product group Chemicals
Estimated Purity99.58
Molecular Weight685.80
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Amiodarone-d4 (hydrochloride) [1216715-80-8]
  • Delivery Days Customer
    10
  • CAS Number
    1216715-80-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.58
  • Molecular Formula
    C25H26D4ClI2NO3
  • Molecular Weight
    685.80
  • Scientific Description
    Amiodarone-d4 (hydrochloride) is the deuterium labeled Amiodarone hydrochloride. Amiodarone hydrochloride, a benzofuran-based Class III antiarrhythmic agent, inhibits WT outwardIhERG tails with an IC50 of ~45 nM[1]. Amiodarone hydrochloride induces cell proliferation and myofibroblast differentiation via ERK1/2 and p38 MAPK signaling in fibroblasts[2]. Amiodarone hydrochloride can be used in the research of both supraventricular and ventricular arrhythmias[1].
  • SMILES
    CCCCC1=C(C(C2=CC(I)=C(OC([2H])([2H])C([2H])([2H])N(CC)CC)C(I)=C2)=O)C3=C(O1)C=CC=C3.Cl
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200