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Amiselimod (hydrochloride)

HY-16734A
MedChem Express
CAS Number942398-84-7
DownloadMSDS
Product group Chemicals
Estimated Purity98.71
Molecular Weight413.90
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Amiselimod (hydrochloride) [942398-84-7]
  • Delivery Days Customer
    10
  • CAS Number
    942398-84-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.71
  • Molecular Formula
    C19H31ClF3NO3
  • Molecular Weight
    413.90
  • Scientific Description
    Amiselimod (MT-1303) hydrochloride is converted to its active metabolite Amiselimod phosphate by sphingosine kinases in vivo. Amiselimod hydrochloride is an orally active and high selectivity sphingosine 1-phosphate receptor-1 ( S1P1 ) agonist, designed to reduce the bradycardia effects associated with fingolimod and other S1P receptor modulators. Amiselimod hydrochloride inhibits chronic colitis via inhibiting infiltration of colitogenic Th1 and Th17 cells into the colon. Amiselimod hydrochloride inhibits lupus nephritis by reducing the infiltration of autoreactive T cells into the kidneys. Amiselimod hydrochloride is promising for research of autoimmune diseases [1] [2] [3] [4] .
  • SMILES
    OCC(CCC1=CC=C(OCCCCCCC)C(C(F)(F)F)=C1)(N)CO.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200