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Amitriptyline-d6 (hydrochloride)

HY-B0527AS
MedChem Express
CAS Number203645-63-0
Product group Chemicals
Estimated Purity99.65
Molecular Weight319.90
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Amitriptyline-d6 (hydrochloride) [203645-63-0]
  • Delivery Days Customer
    10
  • CAS Number
    203645-63-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.65
  • Molecular Formula
    C20H18D6ClN
  • Molecular Weight
    319.90
  • Scientific Description
    Amitriptyline-d 6 (hydrochloride) is the deuterium labeled Amitriptyline hydrochloride. Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 microM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity[1][2][3].
  • SMILES
    [2H]C([2H])([2H])N(C([2H])([2H])[2H])CC/C=C1C2=CC=CC=C2CCC3=CC=CC=C3/1.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200