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Amitriptyline (hydrochloride)

HY-B0527A
MedChem Express
CAS Number549-18-8
Product group Chemicals
Estimated Purity99.94
Molecular Weight313.86
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Amitriptyline (hydrochloride) [549-18-8]
  • Delivery Days Customer
    5
  • CAS Number
    549-18-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.94
  • Molecular Formula
    C20H24ClN
  • Molecular Weight
    313.86
  • Scientific Description
    Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 microM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity[1][2][3].
  • SMILES
    CN(C)CC/C=C1C2=CC=CC=C2CCC3=C\1C=CC=C3.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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