Amivantamab [2171511-58-1]
T77110
CAS Number2171511-58-1
Product group Chemicals
Estimated PuritySDS-PAGE:>95%;SEC-HPLC:97.24%
Molecular Weight145.88 kDa.
Overview
- SupplierTargetMol Chemicals
- Product NameAmivantamab
- Delivery Days Customer19
- CAS Number2171511-58-1
- Category SupplierAntibody
- CertificationResearch Use Only
- Chemical NameAmivantamab
- Estimated PuritySDS-PAGE:>95%;SEC-HPLC:97.24%
- Molecular Weight145.88 kDa.
- Scientific DescriptionAmivantamab (JNJ-61186372) is a humanized antibody that recognizes epidermal growth factor receptor (EGFR) and MET proto-oncogene (MET), with anticancer and anti-tumor activities, preventing ligand binding to EGFR and MET and receptor dimerization that inhibits downstream signal transduction. Amivantamab can induce Fc-dependent endocytosis of macrophages and antibody-dependent cytotoxicity of natural killer cells, and can be used to study metastatic non-small cell lung cancer.
- Shelf life instruction3 years
- Storage Instruction-20°C
- UNSPSC12352203