AMN082 (Standard) [97075-46-2]
HY-103565R
CAS Number97075-46-2
Product group Chemicals
Molecular Weight465.46
Overview
- SupplierMedChem Express
- Product NameAMN082 (Standard) [97075-46-2]
- Delivery Days Customer5
- CAS Number97075-46-2
- Category SupplierCHEMICAL,detergents_surfactants
- CertificationResearch Use Only
- Molecular Weight465.46
- Scientific DescriptionAMN082 (Standard) is the analytical standard of AMN082. This product is intended for research and analytical applications. AMN082, a selective, orally active, and brain penetrant mGluR7 agonist, directly activates receptor signaling via an allosteric site in the transmembrane domain. AMN082 potently inhibits cAMP accumulation and stimulates GTPgammaS binding (EC50 values, 64-290 nM) at transfected mammalian cells expressing mGluR7. AMN082 shows selectivity over other mGluR subtypes and selected ionotropic glutamate receptors. Antidepressant effects[1][2].
- SMILES[H]Cl.[H]Cl.C(NCCNC(C1=CC=CC=C1)C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4
- UNSPSC12352005