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Amodiaquine (dihydrochloride) [69-44-3]

HY-B1322B
MedChem Express
CAS Number69-44-3
Product group Chemicals
Estimated Purity99.97
Molecular Weight428.78
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Amodiaquine (dihydrochloride) [69-44-3]
  • Delivery Days Customer
    5
  • CAS Number
    69-44-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.97
  • Hazard Information
    h302, h315, h319, h335
  • Molecular Formula
    C20H24Cl3N3O
  • Molecular Weight
    428.78
  • Scientific Description
    Amodiaquine dihydrochloride (Amodiaquin dihydrochloride), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor with a Ki of 18.6 nM. Amodiaquine dihydrochloride is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 microM. Anti-inflammatory effect[1][2][3][4][5].
  • SMILES
    [H]Cl.[H]Cl.OC1=CC=C(NC2=CC=NC3=CC(Cl)=CC=C23)C=C1CN(CC)CC
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200