AMPK activator 8 [1852451-96-7]

MedChem Express

AMPK activator 8 [1852451-96-7]

10

1852451-96-7

Research Use Only

C25H21ClN2O6

480.90

AMPK activator 8 (compound 2) is an AMP-activated protein kinase (AMPK) activator with EC50s of 11, 27, 4, 2, and 4 nM for rAMPK alpha1beta1gamma1, rAMPK alpha2beta1gamma1, rAMPK alpha1beta2gamma1, rAMPK alpha2beta2gamma1, rAMPK alpha2beta2gamma3, respectively. AMPK activator 8 can be used for the research of type 2 diabetes[1].

ClC1=C(C2=CC=C(C3=C(C=CC=C3O)O)C=C2)C=C4NC(O[C@H]5[C@]6([H])[C@]([C@@H](CO6)O)([H])OC5)=NC4=C1

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