Western blot analysis of extracts of various cell lines using PRKAB2 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using PRKAB2 Polyclonal Antibody at 1:1000 dilution.
AMPK beta2 Polyclonal Antibody
E-AB-61427
Product group Antibodies
Overview
- SupplierElabscience
- Product NameAMPK beta2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
- UNSPSC12352203