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Western blot analysis of extracts of various cell lines using PRKAB2 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using PRKAB2 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using PRKAB2 Polyclonal Antibody at 1:1000 dilution.

AMPK beta2 Polyclonal Antibody

E-AB-61427
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    AMPK beta2 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
  • UNSPSC
    12352203