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AMPK gamma 1 antibody

Research Use Only
GTX101661
GeneTex
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetPRKAG1
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Overview

  • Supplier
    GeneTex
  • Product Name
    AMPK gamma 1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.33 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID5571
  • Target name
    PRKAG1
  • Target description
    protein kinase AMP-activated non-catalytic subunit gamma 1
  • Target synonyms
    5'-AMP-activated protein kinase subunit gamma-1; 5'-AMP-activated protein kinase, gamma-1 subunit; AMPK gamma1; AMPK gamma-1 chain; AMPKG; protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP54619
  • Protein Name
    5'-AMP-activated protein kinase subunit gamma-1
  • Scientific Description
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK. Lin YY et al., 2012 Feb 8, Nature
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