AMPK gamma 1 antibody
GTX101661
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetPRKAG1
Overview
- SupplierGeneTex
- Product NameAMPK gamma 1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.33 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID5571
- Target namePRKAG1
- Target descriptionprotein kinase AMP-activated non-catalytic subunit gamma 1
- Target synonyms5'-AMP-activated protein kinase subunit gamma-1; 5'-AMP-activated protein kinase, gamma-1 subunit; AMPK gamma1; AMPK gamma-1 chain; AMPKG; protein kinase, AMP-activated, gamma 1 non-catalytic subunit
- HostRabbit
- IsotypeIgG
- Protein IDP54619
- Protein Name5'-AMP-activated protein kinase subunit gamma-1
- Scientific DescriptionThe protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK. Lin YY et al., 2012 Feb 8, NatureRead more