Amuvatinib

MedChem Express

Amuvatinib [850879-09-3]

10

850879-09-3

Research Use Only

99.47

C23H21N5O3S

447.51

Amuvatinib (MP470) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit , PDGFRalpha , Flt3 , c-Met and c-Ret . Amuvatinib (MP470) is also a DNA repair suppressor through suppression of DNA repair protein RAD51 , thereby disrupting DNA damage repair [1] [2] [3] . Antineoplastic activity [4] .

S=C(N1CCN(C2=C3OC4=CC=CC=C4C3=NC=N2)CC1)NCC5=CC=C6OCOC6=C5

-20°C,2°C to 8°C

12352200