ProductsBack/Amylin Receptor 3 (AMY3R)/CRE Luciferase Reporter HEK293 Cell Line

Amylin Receptor 3 (AMY3R)/CRE Luciferase Reporter HEK293 Cell Line

Name: Amylin Receptor 3 (AMY3R)/CRE Luciferase Reporter HEK293 Cell Line
SKU: 83544_B75
Availability: BackOrder

83544

CategoryCells Cell Lines

Product group Cell Culture

Overview

Supplier
BPS Bioscience
Product Name
Amylin Receptor 3 (AMY3R)/CRE Luciferase Reporter HEK293 Cell Line
Delivery Days Customer
23
Certification
Research Use Only
Gene ID3375
Target name
IAPP
Target description
islet amyloid polypeptide
Target synonyms
DAP, IAP, islet amyloid polypeptide, Islet amyloid polypeptide (diabetes-associated peptide; amylin), amylin, diabetes-associated peptide, insulinoma amyloid peptide
Protein IDP10997
Protein Name
Islet amyloid polypeptide
Scientific Description
The Amylin Receptor 3 (AMY3R)/CRE Luciferase Reporter HEK293 Cell Line is a HEK293 cell line engineered to express CALCR (calcitonin receptor, NM_001164737.3) and RAMP3 (receptor activity modifying protein 3, NM_005856.3), delivered into CRE/CREB Luciferase Reporter HEK293 Cell Line (cAMP/PKA Signaling Pathway) (#60515), which expresses a firefly luciferase reporter driven by a multimerized cAMP response element (CRE). Activation of the receptor in these cells can be monitored by measuring luciferase activity. This cell line was validated in dose-response assays using the peptide agonists Amylin, Calcitonin, Pramlintide, Cagrilintide, and Eloralintide. Purchase of this cell line is for research purposes only; commercial use requires a separate license.
Storage Instruction
Liquid Nitrogen
UNSPSC
41116106
Species
Human