Angiotensin I/II/III antibody [B938M]

GeneTex

Angiotensin I/II/III antibody [B938M]

9

Crossreacts with angiotensin I and III in ELISA. Incomplete mapping indicatesreactivity is to a conserved region of all angiotensin molecules (AI/II, a.a. 3-8, Sequence: Val-Tyr-Ile-His-Pro).

ELISA: 1:10-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ELISA

Research Use Only

Monoclonal

B938M

1 mg/ml

Unconjugated

AGT

angiotensinogen

alpha-1 antiproteinase, antitrypsin; angiotensin I; angiotensin II; angiotensinogen; ANHU; fetal-liver predominant transporter 1; hFLT1; pre-angiotensinogen; serine (or cysteine) proteinase inhibitor; serpin A8; serpin peptidase inhibitor, clade A, member 8; SERPINA8

Mouse

IgG1

Angiotensinogen

The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203