IHC-P analysis of human cirrhosis tissue section using GTX02046 Angiotensinogen antibody [034]. Dilution : 1:200
Angiotensinogen antibody [034]
GTX02046
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetAGT
Overview
- SupplierGeneTex
- Product NameAngiotensinogen antibody [034]
- Delivery Days Customer9
- Antibody SpecificityIt has cross-reactivity with human SERPINA1 protein, human SERPINA3 protein, human SERPINA5 protein, human SERPINC1 protein, human SERPIND1 protein, human SERPINF2 protein, human SERPING1 protein, and human SERPINI1 protein in ELISA assay.
- Application Supplier NoteIHC-P: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID34
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID183
- Target nameAGT
- Target descriptionangiotensinogen
- Target synonymsalpha-1 antiproteinase, antitrypsin; angiotensin I; angiotensin II; angiotensinogen; ANHU; fetal-liver predominant transporter 1; hFLT1; pre-angiotensinogen; serine (or cysteine) proteinase inhibitor; serpin A8; serpin peptidase inhibitor, clade A, member 8; SERPINA8
- HostRabbit
- IsotypeIgG
- Protein IDP01019
- Protein NameAngiotensinogen
- Scientific DescriptionThe protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203