Animal-Free BDNF, Human (His)

MedChem Express

Animal-Free BDNF, Human (His)

10

Research Use Only

98.0

BDNF

brain derived neurotrophic factor

ANON2, BULN2, neurotrophic factor BDNF precursor form, abrineurin, neurotrophin, proBDNF

Neurotrophic factor BDNF precursor form

Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin that belongs to NGF-beta family. BDNF can bind to its high affinity receptor TrkB and activates signal transduction cascades (IRS1/2, PI3K, Akt)[1]. BDNF can also bind to the p75NTR, but the affinity for the p75NTR receptor is lower than for TrkB[2]. BDNF is a neurotransmitter modulator, and is vital in maturation, survival and differentiation of neuronal populations during development. BDNF also participates in neuronal plasticity, which is essential for learning and memory. BDNF is widely expressed in the CNS[1]. Animal-Free BDNF Protein, Human/Mouse (His) is an animal-free recombinant human/muose BDNF (H129-R247) with C-terminal His tag, which is produced in E.coli.This product is for cell culture use only.

-20°C

41116100

Human