Bio-Connect

ANK3 Polyclonal Antibody

Research Use Only
RD76705A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetANK3
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    ANK3 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.9 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID288
  • Target name
    ANK3
  • Target description
    ankyrin 3
  • Target synonyms
    ankyrin 3, node of Ranvier (ankyrin G); ankyrin-3; ANKYRIN-G; MRT37
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203