Annexin V (human) (rec.) (FITC)
AG-40B-0005F
Overview
- SupplierAdipoGen Life Sciences
- Product NameAnnexin V (human) (rec.) (FITC)
- Delivery Days Customer10
- CertificationResearch Use Only
- ConjugateFITC
- Estimated Purity>95%
- Protein IDP08758
- Protein NameAnnexin A5
- Scientific DescriptionAnnexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the annexin V affinity assay to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death. - Protein. Recombinant human annexin V fused to a GST-tag. Source: E. coli. Liquid. In PBS, pH 7.4, containing 0.02% sodium azide. Binds to phosphatidylserine (PS). Purity: >95% (SDS-PAGE). Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the annexin V affinity assay to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
- Storage Instruction2°C to 8°C
- UNSPSC12352202