
Immunofluorescence staining of HepG2 cells with CSB-PA679761LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
ANO6 Antibody
CSB-PA679761LA01HU
ApplicationsImmunoFluorescence, ELISA
Product group Antibodies
TargetANO6
Overview
- SupplierCusabio
- Product NameANO6 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID196527
- Target nameANO6
- Target descriptionanoctamin 6
- Target synonymsanoctamin-6; BDPLT7; SCAN channel; SCTS; small-conductance calcium-activated nonselective cation channel; TMEM16F; transmembrane protein 16F
- HostRabbit
- IsotypeIgG
- Protein IDQ4KMQ2
- Protein NameAnoctamin-6
- Scientific DescriptionSmall-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203