Chemical Structure
Chemical Structure
Anomalin A [548740-86-9]
AG-CN2-0006
Overview
- SupplierAdipoGen Life Sciences
- Product NameAnomalin A
- Delivery Days Customer10
- CAS Number548740-86-9
- CertificationResearch Use Only
- Estimated Purity>97%
- Molecular FormulaC14H10O6
- Molecular Weight274.1
- Scientific DescriptionAntiproliferative agent against selected cancer cell lines. Inhibits protein kinases ALK, ARK5, Aurora-B, AXL, FAK, IGF1-R, MET, PIM1, PLK1, PRK1, SRC, and VEGF-R2 with IC50 values between 0.3 and 75.7microM, most probably contributing to the antiproliferative activity. Shown to inhibit VEGF-A dependent endothelial cells sprouting with IC50 value of 1.8microM corresponding to its in vitro inhibitory activity against VEGF-R2 protein kinase (IC50=0.8microM). Lck (p56lck; lymphocyte specific tyrosine kinase) inhibitor. Antioxidant. DPPH radical scavenger. - Chemical. CAS: 548740-86-9. Formula: C14H10O6. MW: 274.1. Isolated from marine fungus Arthrinium sp. Lck (p56lck; lymphocyte specific tyrosine kinase) inhibitor. Antioxidant. DPPH radical scavenger.
- SMILES[H]C1=C(O)C(O)=C(C)C2=C1OC1=C(C(O)=CC(O)=C1)C2=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
References
- Two new xanthone derivatives from the algicolous marine fungus Wardomyces anomalus: A. Abdel-Lateff, et al.; J. Nat. Prod. 66, 706 (2003)