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ANP antibody

GTX109255
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetNPPA
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Overview

  • Supplier
    GeneTex
  • Product Name
    ANP antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.46 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4878
  • Target name
    NPPA
  • Target description
    natriuretic peptide A
  • Target synonyms
    ANF, ANP, ATFB6, ATRST2, CDD, CDD-ANF, CDP, PND, natriuretic peptides A, atrial natriuretic factor prohormone, atrial natriuretic peptide prohormone, atriopeptigen, atriopeptin, cardiodilatin-related peptide, cardionatrin, natriuretic peptide precursor A, preproANP, preproCDD-ANF, prepronatriodilatin, proANF, proANP
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP01160
  • Protein Name
    Natriuretic peptides A
  • Scientific Description
    The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Nandi SS, Katsurada K, Mahata SK, et al. Neurogenic Hypertension Mediated Mitochondrial Abnormality Leads to Cardiomyopathy: Contribution of UPR(mt) and Norepinephrine-miR- 18a-5p-HIF-1α Axis. Front Physiol. 2021,12:718982. doi: 10.3389/fphys.2021.718982
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  • Zhao T, Kee HJ, Bai L, et al. Selective HDAC8 Inhibition Attenuates Isoproterenol-Induced Cardiac Hypertrophy and Fibrosis via p38 MAPK Pathway. Front Pharmacol. 2021,12:677757. doi: 10.3389/fphar.2021.677757
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  • Wen J, Shen J, Zhou Y, et al. Pyrroloquinoline quinone attenuates isoproterenol hydrochloride‑induced cardiac hypertrophy in AC16 cells by inhibiting the NF‑κB signaling pathway. Int J Mol Med. 2020,45(3):873-885. doi: 10.3892/ijmm.2020.4463
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  • Jia D, Hou L, Lv Y, et al. Postinfarction exercise training alleviates cardiac dysfunction and adverse remodeling via mitochondrial biogenesis and SIRT1/PGC-1α/PI3K/Akt signaling. J Cell Physiol. 2019,234(12):23705-23718. doi: 10.1002/jcp.28939
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  • Sun S, Kee HJ, Ryu Y, et al. Gentisic acid prevents the transition from pressure overload-induced cardiac hypertrophy to heart failure. Sci Rep. 2019,9(1):3018. doi: 10.1038/s41598-019-39423-8
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  • Al-Attar R, Storey KB. Effects of anoxic exposure on the nuclear factor of activated T cell (NFAT) transcription factors in the stress-tolerant wood frog. Cell Biochem Funct. 2018,36(8):420-430. doi: 10.1002/cbf.3362
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  • Kesherwani V, Nandi SS, Sharawat SK, et al. Hydrogen sulfide mitigates homocysteine-mediated pathological remodeling by inducing miR-133a in cardiomyocytes. Mol Cell Biochem. 2015,404(1-2):241-50. doi: 10.1007/s11010-015-2383-5
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  • Luu BE, Tessier SN, Duford DL, et al. The regulation of troponins I, C and ANP by GATA4 and Nkx2-5 in heart of hibernating thirteen-lined ground squirrels, Ictidomys tridecemlineatus. PLoS One. 2015,10(2):e0117747. doi: 10.1371/journal.pone.0117747
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