Anti-14-3-3 alpha+beta Antibody

HUABIO

Anti-14-3-3 alpha+beta Antibody

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

GW128, HEL-S-1, HS1, KCIP-1, YWHAA, 14-3-3 protein beta/alpha, 14-3-3 alpha, epididymis secretory protein Li 1, protein 1054, protein kinase C inhibitor protein-1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

Rabbit

IgG

14-3-3 protein beta/alpha

The 14-3-3 proteins are a family of proteins involved in the regulation of apoptosis, mitogenic signaling and cell-cycle checkpoints. The 14-3-3 proteins are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. Through binding Bad, 14-3-3 prevents apoptosis by sequestering Bad to the cytosol. The 14-3-3 proteins are also Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. They bind to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161