Anti-14-3-3 sigma Mouse mAb

PTM BIO

Anti-14-3-3 sigma Mouse mAb

5

Western Blot, ImmunoHistoChemistry Paraffin

WB, IHC-P

Research Use Only

Monoclonal

12622

Unconjugated

Mouse

IgG

14-3-3 protein sigma

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a Phosphorylatedserine or Phosphorylatedthreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

Stable for 12 months from date of receipt/reconstitution.

Human

Human

Protein G purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203