Anti-17-Hydroxyprogesterone [101.B11.1]

Absolute Antibody

Anti-17-Hydroxyprogesterone [101.B11.1]

7

The antibody binds specifically to 17-OHP, an endogenous progestogen which acts as a chemical intermediate in the synthesis of steroid hormones such as corticosteroids, androgens and estrogens. 17-OHP levels are extremely high in patients who suffer from congenital adrenal hyperplasia (CAH), a disorder of the adrenal glands caused by the deficiency of 21-hydroxylase which catalyses the production of cortisol. This results in the accumulation of the cortisol precursors, and in particular of 17-OHP. Monoclonal antibodies that bind specifically to 17-OHP can therefore be used to measure 17-OHP levels in the diagnosis of CAH.

ELISA

ELISA; EIA

Research Use Only

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203