Anti-2-Hydroxyisobutyryllysine Antibody Conjugated Agarose Beads

PTM BIO

Anti-2-Hydroxyisobutyryllysine Antibody Conjugated Agarose Beads

5

IAP

Research Use Only

Mix

Agarose

IgG

Histones are subjected to a variety of enzyme catalyzed modifications, including acetylation, methylation, ubiquitylation, etc. 2-Hydroxyisobutyrylation of lysine is a newly identified reversible modification controlling chromosome structure and gene transcription. The reversible lysine 2-hydroxyisobutyrylation has been well demonstrated in eukaryotic histones from worm to human. The unique structure and genomic localization of histone lysine 2-hydroxyisobutyrylation suggest that it is mechanistically and functionally different from histone lysine acetylation.

Stable for 12 months from date of receipt.

All Species

All

Store at -20°C. Avoid freeze/thaw cycles.

12352203