Anti-2.4[2.8]2.4-linked Kdo tetrasaccharide [S48-18]

Absolute Antibody

Anti-2.4[2.8]2.4-linked Kdo tetrasaccharide [S48-18]

9

This antibody is specific for 2.4[2.8]2.4-linked Kdo tetrasaccharide. Which is a partial structure of chlamydial lipopolysaccharide (LPS).

An ELISA was performed on neoglycoconjugates using the mouse version of this antibody, it showed the strongest binding to alphaKdo(2 to 4)alphaKdo(2 to 4)alphaKdo and alphaKdo(2 to 4)alphaKdo(2 to 4)alphaKdo(2 to 6)betaGlcNAc. ELISA was also performed on LPS antigens and bacterial antigens using the mouse version of this antibody, it bound most strongly to Chl. psittaci EB and Chl. psittaci LPS (Brade et al, 2000; pmid:11521056). The scFv version of this antibody was used for an ELISA on neoglycoconugates, the antibody bound to 2.4/2.4PS4P and HS4P quite well but bound less well to 2.8/2.4PS4P (Gerstenbruch et al, 2010; pmid:20022906).

ELISA

Research Use Only

Monoclonal

S48-18

Mouse

IgG1

Other Species

-20°C,2°C to 8°C

12352203