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Anti-5T4 [m1002]

Ab02337-10.0
Absolute Antibody
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
TargetTPBG
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-5T4 [m1002]
  • Delivery Days Customer
    7
  • Application Supplier Note
    5T4 is an oncofetal antigen expressed in a number of carcinomas including colorectal, ovarian, renal, non-small cell lung and gastric carcinomas, while its expression in normal adult tissues is limited. This antibody is recomended for diagnosis of cancer in a patient. Fab version of this antibody bound to 5T4 with an EC50 of 2 nmol/L, as measured by ELISA. This antibody was also capable of binding native 5T4 associated with cell surfaces. The binding of m1001 to surface expressed 5T4 on A498 cells was confirmed using flow cytometry (WO2016022939).
  • Applications
    Flow Cytometry, ELISA
  • Applications Supplier
    ELISA, FC
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    m1002
  • Gene ID7162
  • Target name
    TPBG
  • Target description
    trophoblast glycoprotein
  • Target synonyms
    5T4; 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; 5T4AG; M6P1; trophoblast glycoprotein; WAIF1; wnt-activated inhibitory factor 1
  • Host
    Human
  • Isotype
    IgG1
  • Protein IDQ13641
  • Protein Name
    Trophoblast glycoprotein
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    The original antibody was generated from phage display libraries constructed using healthy human blood of 40 doners and cord blood of 10 doners and biopanning them against recombinant 5T4-Fc fusion protein conjugated to magnetic beads.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203

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