anti-ABCD4 antibody

Arigo Biolaboratories

anti-ABCD4 antibody

23

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

ABCD4

ATP binding cassette subfamily D member 4

ABC41, EST352188, MAHCJ, P70R, P79R, PMP69, PXMP1L, lysosomal cobalamin transporter ABCD4, 69 kDa peroxisomal ABC-transporter, ATP-binding cassette sub-family D member 4, ATP-binding cassette, sub-family D (ALD), member 4, PMP70-related protein, PXMP1-L, peroxisomal membrane protein 69

Goat

IgG

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008]

Canine, Human, Mouse, Rat

-20°C

12352203