Anti-ABCG2 Antibody [JF0994]

HUABIO

Anti-ABCG2 Antibody [JF0994]

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,FC

Research Use Only

Monoclonal

JF0994

1 mg/ml

Unconjugated

ABCG2

ATP binding cassette subfamily G member 2 (JR blood group)

ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, CDw388, EST157481, GOUT1, MRX, MXR, MXR-1, MXR1, UAQTL1, broad substrate specificity ATP-binding cassette transporter ABCG2, ABC transporter, ATP binding cassette subfamily G member 2 (Junior blood group), ATP-binding cassette transporter G2, ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group), ATPbinding cassette transporter ABCG2, breast cancer resistance protein, broad substrate specificity ATP-binding cassette transporter ABCG2 isoform 1 (Junior blood group), mitoxantrone resistance-associated protein, multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2, placenta specific MDR protein, placenta-specific ATP-binding cassette transporter, urate exporter

Rabbit

IgG

Broad substrate specificity ATP-binding cassette transporter ABCG2

ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes through the energy of ATP hydrolysis. The ABC half-transporter, ABCG2, is also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1). ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Under normal conditions, ABCG2 may serve a protective function by removing toxins from the cell, and plays an important role in regulating stem cell differentiation. ABCG2 is responsible for the side population (SP) phenotype and is widely expressed in a large variety of stem cells, making it an important stem cell marker. ABCG2 may have N-linked glycosylation and may dimerize in vivo. ABCG2 is abundantly expressed in placenta, liver, intestine and stem cells.

Human, Mouse

Human,Mouse

-20°C,2°C to 8°C

41116161