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Anti Achaete-Scute Homolog 1 (ASH-1/MASH-1) pAb (Rabbit, Antiserum)

Anti Achaete-Scute Homolog 1 (ASH-1/MASH-1) pAb (Rabbit, Antiserum)

Research Use Only
CAC-SK-T01-003
Cosmo Bio USA
Product group Antibodies
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Overview

  • Supplier
    Cosmo Bio USA
  • Product Name
    Anti Achaete-Scute Homolog 1 (ASH-1/MASH-1) pAb (Rabbit, Antiserum)
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Scientific Description
    Component of the RPD3C(L) histone deacetylase complex (HDAC). Responsible for the deacetylation of lysine residues on the N-terminal tails of core histones (H2A, H2B, H3 and H4). Histone deacetylation is a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. ASH1 is necessary to repress HO in daughter cells to block mating-type switching through its binding to HO promoter 5-YTGAT-3 sites. It is also involved in pseudohyphal growth. References: Yoshida et al. (2001) Proprotein convertase PACE4 is down-regulated by the basic helix-loop-hekix transcription factor hash-1 and MASH-1. Biochem. J. 360, 683-689.
  • UNSPSC
    12352203