Western blot with extracellular domains (ecd) of different related human receptors (50ng per lane) reveals that anti-Activin Receptor IIB, pAb (IG-510) (Prod. No. AG-25T-0114) (dilution 1:5000) specifically recoginzes ACTR-IIB under nonreducing (-betaME, lef
anti-Activin Receptor IIB, pAb (IG-510)
AG-25T-0114
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetAcvr2b
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-Activin Receptor IIB, pAb (IG-510)
- Delivery Days Customer10
- Antibody SpecificityRecognizes the extracellular domain of human and mouse ACTR-IIB. Does not cross-react with related human proteins ActR-IIecd, BMPR-IIecd, BMPR-IAecd, BMPR-IBecd or ActR-Iecd.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration500 ug/ml
- FormulationLiquid
- Gene ID11481
- Target nameAcvr2b
- Target descriptionactivin receptor IIB
- Target synonyms4930516B21Rik; Act; activin receptor type IIB; activin receptor type-2B; ActRIIB; AI047905
- HostRabbit
- Protein IDP27040
- Protein NameActivin receptor type-2B
- Scientific DescriptionActivin Receptor IIB (ACTR-IIB) is a transmembrane receptor that forms an activin receptor complex with activin type-1 receptors (ACVR1, ACVR1B or ACVR1c). ACTR-IIB transduces the activin signal from the cell surface to the cytoplasm and regulates therefore many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary. - Polyclonal Antibody. Recognizes the extracellular domain of human and mouse ACTR-IIB. Does not cross-react with related human proteins ActR-IIecd, BMPR-IIecd, BMPR-IAecd, BMPR-IBecd or ActR-Iecd. Source: Rabbit. Applications: ELISA, WB. Liquid. In PBS with 1 mg/ml BSA and 0.02% sodium azide. Activin Receptor IIB (ACTR-IIB) is a transmembrane receptor that forms an activin receptor complex with activin type-1 receptors (ACVR1, ACVR1B or ACVR1c). ACTR-IIB transduces the activin signal from the cell surface to the cytoplasm and regulates therefore many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary.
- ReactivityHuman, Mouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203