anti-Akt phospho (Thr342) antibody

Arigo Biolaboratories

anti-Akt phospho (Thr342) antibody

23

Western Blot

Research Use Only

Polyclonal

Unconjugated

Akt1

Akt1

Akt; Akt kinase; AKT/PKB; Akt1; Akt1|PKB; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; DAKT; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; dAkt1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; Dpkb; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; pAkt; p-Akt; PKB; PKB/AKT; PKB/dAKT; protein kinase B; RAC; RAC serine/threonine protein kinase; RacPK; related to PKA to PKC protein kinases; related to the A and C kinases

Rabbit

IgG

Phosphorylated

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]

Drosophila

-20°C

12352203